Integrated circuits (ICs) are the basis of the information industry and play an important role in social and economic development. To systematically understand the innovation and development of IC in China and overcome the major challenges of research and development (R & D) and coordinated development in the new era, we collate the development status of global IC and analyze the technology development trends and the global cooperation among major R & D organizations by the bibliometric method. It is found that leading IC enterprises are the main entities of technology innovation in this field, and they form a lateral cooperation mode. Meanwhile, large-scale R & D centers with enterprises or research institutes at the core play a critical role in developing key general-purpose technology, and they present the cooperation and development trends of coexisted globalization and regionalization. Moreover, relevant policy and development suggestions are put forward given the R & D status in China’s IC and the construction status of national strategic science and technology forces.